Description

(3α)-3-[(4-Nitrobenzoyl)Oxy]Androst-5-En-17-One is a high-purity steroid derivative, specifically a 3β-hydroxy-δ5-steroid esterified with 4-nitrobenzoic acid. This compound is a critical pharmaceutical intermediate and research chemical used in the synthesis and development of more complex steroid-based active pharmaceutical ingredients (APIs). It is essential for R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on steroid chemistry, metabolic pathway studies, and novel therapeutic agent discovery.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of steroidal drugs and hormones.
• Research & Development: Used as a reference standard or starting material in academic and industrial research exploring steroid biochemistry and pharmacology.
• API Synthesis: Serves as a precursor in the production of more complex steroid-based Active Pharmaceutical Ingredients (APIs).
• Metabolic Studies: Employed in laboratory studies to investigate steroid metabolism, enzyme inhibition, and receptor binding activities.
• Process Chemistry: Utilized in route scouting and process optimization for the commercial-scale manufacture of steroid compounds.

Basic Information

Product Name	(3α)-3-[(4-Nitrobenzoyl)Oxy]Androst-5-En-17-One
CAS No.	1383292-25-8
Molecular Formula	C27H33NO5
Molecular Weight	451.56 g/mol
Synonyms	3β-(4-Nitrobenzoyloxy)androst-5-en-17-one; 17-Oxoandrost-5-en-3β-yl 4-nitrobenzoate; Androst-5-en-17-one, 3-[(4-nitrobenzoyl)oxy]-, (3β)-; 4-Nitrobenzoic acid (3β)-17-oxoandrost-5-en-3-yl ester
EINECS	Contact for details

Quality Control

Our (3α)-3-[(4-Nitrobenzoyl)Oxy]Androst-5-En-17-One is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality system is designed to support cGMP requirements for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.