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Gdc-0084 CAS NO 1382979-44-3
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CAS No.:1382979-44-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Gdc-0084 CAS NO 1382979-44-3 is a potent and selective small molecule inhibitor targeting key signaling pathways in oncology research. This high-purity compound is critical for advancing pharmaceutical discovery and preclinical development programs. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel cancer therapeutics.
Application
- Pharmaceutical R&D: A key reference standard and active pharmaceutical ingredient (API) intermediate in oncology drug discovery.
- Biochemical Research: Used as a potent tool compound for studying specific kinase inhibition and related cellular signaling mechanisms in vitro.
- Preclinical Studies: Essential for pharmacokinetic (PK), pharmacodynamic (PD), and efficacy studies in animal models of cancer.
- Mechanism of Action (MoA) Analysis: Employed to validate drug targets and understand resistance pathways in cancer cell lines.
- High-Throughput Screening (HTS): Serves as a control or benchmark compound in screening assays for identifying new drug candidates.
- Combinatorial Therapy Research: Investigated for potential synergistic effects when used in combination with other therapeutic agents.
Basic Information
| Product Name | Gdc-0084 |
| CAS No. | 1382979-44-3 |
| Molecular Formula | Contact for details |
| Molecular Weight | Contact for details |
| Synonyms | GDC-0084; GDC0084; 1382979-44-3; PVSRIPO; (S)-N-(5-((6-(2-Hydroxypropan-2-yl)pyridin-3-yl)methyl)-2-morpholinothieno[3,2-d]pyrimidin-4-yl)-3-methylbut-2-enamide; RG-7666; RG7666; GDC 0084 |
| EINECS | Contact for details |
Quality Control
Our Gdc-0084 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under inert atmosphere.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white solid |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥98.0% |
| Water Content (KF) | ≤0.5% |
| Residual Solvents (GC) | Complies with ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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