Description

2,4-Difluoro-6-Methylbenzyl Alcohol is a fluorinated benzyl alcohol derivative, a versatile and high-value building block in advanced organic synthesis. Its molecular structure, featuring strategically placed fluorine atoms and a reactive hydroxymethyl group, makes it a critical intermediate for creating compounds with enhanced biological activity and specific physicochemical properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing fluorinated drug candidates for oncology, CNS disorders, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where fluorine substitution can improve efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a precursor in the manufacture of fluorinated components for electronic display materials and organic light-emitting diodes (OLEDs).
• Advanced Polymer Chemistry: Employed as a monomer or modifier to introduce fluorine into polymer backbones, enhancing material properties like chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis & Catalysis: A valuable reagent in cross-coupling reactions and as a ligand precursor in organometallic catalysis and asymmetric synthesis.
• Life Science Research: Utilized in medicinal chemistry programs for structure-activity relationship (SAR) studies and as a probe molecule in biochemical assays.

Basic Information

Product Name	2,4-Difluoro-6-Methylbenzyl Alcohol
CAS No.	1379220-74-2
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	(2,4-Difluoro-6-methylphenyl)methanol; 6-(Hydroxymethyl)-2,4-difluoro-1-methylbenzene; 2,4-Difluoro-6-methylbenzenemethanol; α,2,4-Trifluoro-6-methyltoluene (deprecated); 2,4-Difluoro-6-methyl-benzylalcohol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Production follows cGMP principles where applicable, and every batch is analyzed using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.