Description

6-n-Acyl-6-n-Methyl-2'-Deoxyadenosine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is critical for the development of novel therapeutic agents and diagnostic tools, particularly in the fields of oncology and virology. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of next-generation nucleotide-based drugs.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand DNA repair mechanisms and polymerase activity.
• Proteomics & Genomics: Serves as a modified base for developing advanced probes and tools for nucleic acid sequencing and detection.
• Antisense Oligonucleotide Synthesis: Incorporated into oligonucleotide chains to enhance stability, binding affinity, and therapeutic efficacy.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic properties of drug candidates.
• Academic Research: Fundamental studies in organic chemistry and nucleoside chemistry for developing new synthetic methodologies.

Basic Information

Product Name	6-n-Acyl-6-n-Methyl-2'-Deoxyadenosine
CAS No.	1377950-60-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	6-N-Acyl-6-N-methyl-2'-deoxyadenosine; 6-(Acylmethyl)amino-2'-deoxyadenosine; N6-Acyl-N6-methyl-2'-deoxyadenosine; Modified 2'-Deoxyadenosine Derivative; 6-Substituted-2'-Deoxyadenosine; dA(N6-Me-Acyl) Phosphoramidite precursor; Nucleoside Building Block CAS 1377950-60-1
EINECS	Contact for details

Quality Control

Our 6-n-Acyl-6-n-Methyl-2'-Deoxyadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.