Description

2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzyl Alcohol, 97% is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique trifluoromethyl and methoxy substitution pattern, which imparts desirable electronic and steric properties to target molecules. It is primarily needed by pharmaceutical, agrochemical, and material science R&D teams for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated liquid crystals and organic light-emitting diode (OLED) materials, contributing to improved electro-optical properties.
• Polymer & Resin Modifier: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and surface properties.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions like Suzuki or Buchwald-Hartwig couplings to construct complex biaryl systems.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzyl Alcohol, 97%
CAS No.	1373921-03-9
Molecular Formula	C10H8F4O2
Molecular Weight	236.16 g/mol
Synonyms	[2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl]methanol; (2-Fluoro-5-methoxy-3-trifluoromethylphenyl)methanol; 2-Fluoro-5-methoxy-α-(trifluoromethyl)benzenemethanol; 1-(2-Fluoro-5-methoxy-3-(trifluoromethyl)phenyl)methanol; 2-Fluoro-5-methoxy-3-(trifluoromethyl)benzyl alcohol; α-(Trifluoromethyl)-2-fluoro-5-methoxybenzenemethanol
EINECS	Contact for details

Quality Control

Our 2-Fluoro-5-Methoxy-3-(Trifluoromethyl)Benzyl Alcohol, 97% is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure it meets the declared 97% minimum purity and consistent impurity profile. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, well-ventilated area. This material is easily oxidized and should be handled with care to minimize exposure to air. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.