Description

4-Butoxy-2,6-Difluorobenzoylchloride is a high-purity, specialized benzoyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, where the benzoyl chloride group acts as a potent acylating agent and the butoxy and difluoro substituents confer unique electronic and steric properties to the final molecule. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a difluorobenzoyl moiety.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a building block for fluorine-containing liquid crystal compounds used in display technologies.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce fluorinated aromatic units into high-performance polymers.
• Organic Electronics: Intermediate in the production of materials for organic light-emitting diodes (OLEDs) and semiconductors.
• Custom Synthesis & R&D: A valuable reagent for medicinal chemistry and process research in contract research and manufacturing organizations (CROs/CMOs).

Basic Information

Product Name	4-Butoxy-2,6-Difluorobenzoylchloride
CAS No.	1373920-74-1
Molecular Formula	C11H11ClF2O2
Molecular Weight	248.65 g/mol
Synonyms	2,6-Difluoro-4-butoxybenzoyl chloride; 4-Butoxy-2,6-difluorobenzoic acid chloride; Benzoic acid, 4-butoxy-2,6-difluoro-, chloride; 4-(Butoxy)-2,6-difluorobenzoyl chloride; 2,6-Difluoro-4-n-butoxybenzoyl chloride; Benzoyl chloride, 4-butoxy-2,6-difluoro-
EINECS	Contact for details

Quality Control

Our 4-Butoxy-2,6-Difluorobenzoylchloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.