Description

1-(5-(7-(3-Morpholinopropoxy)Quinazolin-4-Ylthio)-1,3,4-Thiadiazol-2-Yl)-3-p-Tolylurea is a sophisticated heterocyclic organic compound featuring a quinazoline core linked to a thiadiazole and a urea moiety, representing a high-value chemical intermediate. This compound matters for its role as a key building block in the research and development of novel pharmaceutical agents, particularly in oncology and targeted therapies. It is primarily needed by R&D chemists, process development scientists, and manufacturers in the pharmaceutical and biotechnology industries engaged in the synthesis of complex small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of targeted kinase inhibitors for cancer research.
• Biochemical Research: Used as a reference standard or a probe compound in enzymatic assays and biological pathway studies.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize drug candidate efficacy and selectivity.
• Process Chemistry: Utilized in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and drug discovery.

Basic Information

Product Name	1-(5-(7-(3-Morpholinopropoxy)Quinazolin-4-Ylthio)-1,3,4-Thiadiazol-2-Yl)-3-p-Tolylurea
CAS No.	1370256-78-2
Molecular Formula	C25H27N7O3S2
Molecular Weight	537.66 g/mol
Synonyms	1-(5-((7-(3-Morpholinopropoxy)-4-quinazolinyl)thio)-1,3,4-thiadiazol-2-yl)-3-(4-methylphenyl)urea; 1-(5-(7-(3-Morpholinopropoxy)quinazolin-4-ylthio)-1,3,4-thiadiazol-2-yl)-3-p-tolylurea; 1-(5-((7-(3-Morpholin-4-ylpropoxy)quinazolin-4-yl)thio)-1,3,4-thiadiazol-2-yl)-3-(4-methylphenyl)urea; CAS 1370256-78-2; p-Tolylurea derivative; Quinazolin-4-ylthio-thiadiazole urea.
EINECS	Contact for details

Quality Control

Our 1-(5-(7-(3-Morpholinopropoxy)Quinazolin-4-Ylthio)-1,3,4-Thiadiazol-2-Yl)-3-p-Tolylurea is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.