Description

2-Chloro-6-Cyclobutylpyridine CAS NO 1369827-66-6 is a high-value halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclobutyl substituent adjacent to a reactive chlorine atom, makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used to develop novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands in catalytic and coordination chemistry.
• Material Science: Building block for advanced organic electronic materials and liquid crystals.
• Chemical Biology: Utilized in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific projects requiring complex pyridine chemistry.

Basic Information

Product Name	2-Chloro-6-Cyclobutylpyridine
CAS No.	1369827-66-6
Molecular Formula	C9H10ClN
Molecular Weight	167.64 g/mol
Synonyms	6-Cyclobutyl-2-chloropyridine; 2-Chloro-6-cyclobutylpyridine; Pyridine, 2-chloro-6-cyclobutyl-; 2-Chloro-6-cyclobutyl-pyridine; 1369827-66-6
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Cyclobutylpyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and residual solvent analysis. A Certificate of Analysis (COA) is supplied with each shipment, detailing all relevant specifications. Our quality commitment supports compliance in GMP-oriented synthesis and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.