Description

(R)-7-(Benzyloxy)- 3,4,12,12A-Tetrahydro- 1H-[1,4]Oxazino[3,4- C]Pyrido[2,1-F][1,2,4]- Triazine-6,8-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in medicinal chemistry for the research and development of novel therapeutic agents, particularly as a key chiral building block. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of potential drug candidates, especially in central nervous system (CNS) or anti-infective therapeutic areas.
• Medicinal Chemistry Research: Used as a scaffold or precursor for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in the scale-up and route scouting for the commercial production of complex target molecules.
• Academic Research: Utilized in university and institutional labs for studying novel heterocyclic chemistry, asymmetric synthesis, and reaction mechanisms.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Reference Standard: Can be provided as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(R)-7-(Benzyloxy)- 3,4,12,12A-Tetrahydro- 1H-[1,4]Oxazino[3,4- C]Pyrido[2,1-F][1,2,4]- Triazine-6,8-Dione
CAS No.	1985607-70-2
Molecular Formula	C20H19N3O4
Molecular Weight	365.38 g/mol
Synonyms	(R)-7-(Benzyloxy)-1,2,3,4,12,12a-hexahydro[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione; (7R)-7-(Phenylmethoxy)-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-6,8-dione; Benzyl (R)-7-hydroxy-6,8-dioxo-3,4,12,12a-tetrahydro-1H-[1,4]oxazino[3,4-c]pyrido[2,1-f][1,2,4]triazine-7-carboxylate derivative (related); CAS 1985607-70-2; Advanced Oxazinopyridotriazine Intermediate; Chiral Fused Triazine Derivative.
EINECS	Contact for details

Quality Control

Our (R)-7-(Benzyloxy)- 3,4,12,12A-Tetrahydro- 1H-[1,4]Oxazino[3,4- C]Pyrido[2,1-F][1,2,4]- Triazine-6,8-Dione is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and isomeric purity suitable for demanding pharmaceutical applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.