Description

2-(5-Bromopyridin-2-Yl)-1-(2,4-Difluorophenyl)-2,2-Difluoroethanone is a high-value, multi-fluorinated and brominated organic building block designed for advanced synthetic chemistry. This compound matters because it provides a unique, functionalized scaffold critical for constructing complex molecules in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for applications such as medicinal chemistry, pesticide development, and materials science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the difluoroethanone and bromopyridine motifs for enhanced bioactivity and environmental stability.
• Material Science: Serves as a specialized monomer or cross-linking agent in the creation of advanced polymers with specific optical or electronic properties.
• Chemical Biology Probe Synthesis: Employed to build molecular probes for studying enzyme function and protein-ligand interactions due to its halogenated structure.
• Ligand Development for Catalysis: Acts as a starting material for synthesizing novel, fluorinated ligands used in transition metal catalysis to improve reaction selectivity and efficiency.

Basic Information

Product Name	2-(5-Bromopyridin-2-Yl)-1-(2,4-Difluorophenyl)-2,2-Difluoroethanone
CAS No.	294182-06-2
Molecular Formula	C13H6BrF4NO
Molecular Weight	348.09 g/mol
Synonyms	1-(2,4-Difluorophenyl)-2,2-difluoro-2-(5-bromopyridin-2-yl)ethanone; 2,2-Difluoro-1-(2,4-difluorophenyl)-2-(5-bromo-2-pyridinyl)ethanone; 294182-06-2; 2-(5-Bromo-2-pyridyl)-1-(2,4-difluorophenyl)-2,2-difluoroethanone; 5-Bromo-2-[2,2-difluoro-2-(2,4-difluorophenyl)acetyl]pyridine
EINECS	Contact for details

Quality Control

Our 2-(5-Bromopyridin-2-Yl)-1-(2,4-Difluorophenyl)-2,2-Difluoroethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.