Description

5-Chloro-2-Nitropyridine is a versatile halogenated nitropyridine derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of its functional groups, which enable selective substitution reactions for constructing complex heterocyclic systems. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of antiviral and antibacterial agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its reactive halogen and nitro groups.
• Material Science Research: Serves as a precursor for creating functionalized pyridine ligands used in catalysis and advanced polymers.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of complex organic dyes and colorants.
• Academic & R&D Laboratories: Employed in methodological studies and as a starting material for novel heterocyclic compound libraries.
• Cross-Coupling Reactions: A valuable substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Item	Detail
Product Name	5-Chloro-2-Nitropyridine
CAS No.	52092-47-4
Molecular Formula	C5H3ClN2O2
Molecular Weight	158.54 g/mol
Synonyms	2-Nitro-5-chloropyridine; 5-Chloro-2-nitropyridine; 2-Nitro-5-chloropyridine; 5-Chloro-2-nitro-pyridine; Pyridine, 5-chloro-2-nitro-; 5-Chlor-2-nitropyridin; 5-Chloro-2-nitro-pyridin; 5-Chloro-2-nitropyridine (CAS 52092-47-4)
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Nitropyridine is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation and to minimize degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68 - 72 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.