Description

2-Chloropyridine-n-Oxide is a versatile and high-value heterocyclic building block and key intermediate in organic synthesis. Its unique structure, featuring both a halogen and an N-oxide moiety, makes it a critical precursor for constructing complex molecules in advanced research and development. This compound is essential for pharmaceutical chemists, agrochemical researchers, and material scientists engaged in the synthesis of active pharmaceutical ingredients (APIs), novel crop protection agents, and specialty ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the production of various drug candidates, including kinase inhibitors, anti-infectives, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, leveraging its reactivity for creating novel heterocyclic scaffolds.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized pyridine-based ligands used in homogeneous catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or molecular components for OLEDs and sensors.
• Chemical Research & Development: Utilized in academic and industrial R&D for method development, exploring new C-H functionalization, and cross-coupling reactions.
• Custom Synthesis and Contract Manufacturing: A critical starting material for fine chemical companies offering bespoke synthesis services for complex organic molecules.

Basic Information

Product Name	2-Chloropyridine-n-Oxide
CAS No.	2402-95-1
Molecular Formula	C5H4ClNO
Molecular Weight	129.54 g/mol
Synonyms	2-Chloropyridine 1-Oxide; 2-Chloropyridine N-Oxide; 2-Chloro-1-oxidopyridin-1-ium; Pyridine, 2-chloro-, 1-oxide; 2-Chloropyridine oxide; N-Oxido-2-chloropyridinium; 2-Cl-PyO; 2-Chloropyridinium N-oxide
EINECS	219-290-7

Quality Control

Our 2-Chloropyridine-n-Oxide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, confirming identity, purity, and impurity profiles to meet your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	86 - 90 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.