Description

3-Bromo-4-Methylpyridine is a versatile halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its reactive bromine substituent and the directing influence of its methyl group, enabling precise functionalization for complex molecule construction. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted pyridine cores.
• Agrochemical Synthesis: Used in the development of modern pesticides, herbicides, and fungicides where the bromo-methylpyridine scaffold imparts specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or molecular components for OLEDs and sensors.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying biological pathways and protein function.
• Cross-Coupling Reactions: Acts as a reliable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	3-Bromo-4-Methylpyridine
CAS No.	3430-22-6
Molecular Formula	C6H6BrN
Molecular Weight	172.02 g/mol
Synonyms	4-Methyl-3-bromopyridine; 3-Bromo-4-picoline; 3-Bromo-4-methylpyridine; 3-Bromo-4-methyl-pyridine; 4-Methyl-3-pyridyl bromide; 3-Bromo-4-methylpyridine (major); Pyridine, 3-bromo-4-methyl-
EINECS	222-317-6

Quality Control

Our 3-Bromo-4-Methylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.