Description

2-Butenoyl Chloride, 4-(1-Piperidinyl)-, (2E)- is a specialized organic building block featuring a reactive acid chloride group conjugated with a piperidine moiety. This compound matters as a key intermediate for synthesizing complex molecules, particularly in pharmaceutical research where its structure enables the introduction of specific pharmacophores. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the piperidine ring can contribute to biological activity.
• Chemical Research & Development: Serves as a versatile reagent for introducing the 4-(1-piperidinyl)-2-butenoyl moiety into more complex molecular architectures in academic and industrial labs.
• Ligand and Catalyst Preparation: Employed in the synthesis of specialized ligands or organocatalysts for asymmetric synthesis and other catalytic processes.
• Material Science Precursor: Acts as a monomer or functionalization agent in the development of advanced polymers with tailored properties.

Basic Information

Product Name	2-Butenoyl Chloride, 4-(1-Piperidinyl)-, (2E)-
CAS No.	1369372-07-5
Molecular Formula	C9H14ClNO
Molecular Weight	187.67 g/mol
Synonyms	(2E)-4-(Piperidin-1-yl)but-2-enoyl chloride; 4-Piperidin-1-ylbut-2-enoyl chloride; (E)-4-(1-Piperidinyl)-2-butenoyl chloride; 4-(1-Piperidinyl)-2-butenoyl chloride, (E)-; trans-4-(Piperidin-1-yl)but-2-enoyl chloride; 2-Butenoyl chloride, 4-(1-piperidinyl)-, (E)-; 1369372-07-5; (E)-4-(Piperidin-1-yl)but-2-enoyl chloride
EINECS	Contact for details

Quality Control

Every batch of 2-Butenoyl Chloride, 4-(1-Piperidinyl)-, (2E)- undergoes rigorous analytical testing to ensure identity, purity, and consistency suitable for research and development applications. Our quality commitment includes adherence to in-house specifications developed for high-purity intermediates. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profile is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.