Description

2H-[1,3]Dioxolo[4,5-B]Pyridin-5-Amine is a specialized heterocyclic amine building block of significant interest in advanced organic synthesis. Its unique fused dioxole-pyridine structure makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in catalytic systems for asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers due to its electron-donating amine group and rigid structure.
• Academic & Contract Research: A valuable reagent for methodological studies and the synthesis of complex natural product analogs in university and CRO laboratories.

Basic Information

Product Name	2H-[1,3]Dioxolo[4,5-B]Pyridin-5-Amine
CAS No.	1368345-12-3
Molecular Formula	C7H6N2O2
Molecular Weight	150.14 g/mol
Synonyms	5-Amino-2H-[1,3]dioxolo[4,5-b]pyridine; 2H-[1,3]Dioxolo[4,5-b]pyridin-5-amine; 1,3-Dioxolo[4,5-b]pyridin-5-amine; 5-Amino-1,3-dioxolo[4,5-b]pyridine; 1368345-12-3; 5-Amino-2H-1,3-benzodioxole-6-carbonitrile (related structure); Fused pyridine-dioxole amine
EINECS	Contact for details

Quality Control

Every batch of 2H-[1,3]Dioxolo[4,5-B]Pyridin-5-Amine is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for research chemicals. A detailed Certificate of Analysis (COA) documenting purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.