Description

2H-Pyrazolo[3,4-C]Pyridine, 4,5,6,7-Tetrahydro-2-Methyl- is a high-purity, advanced pharmaceutical intermediate (API) with the CAS number 1368187-49-8. This heterocyclic compound is a critical building block in modern medicinal chemistry, valued for its unique fused pyrazolopyridine scaffold. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for clinical research and drug development.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) and structure-activity relationship (SAR) studies.
• Kinase Inhibitor Development: The pyrazolopyridine core is a privileged structure in the design of potent and selective kinase inhibitors for oncology applications.
• CNS Drug Discovery: Employed in the research and development of therapeutics targeting neurological disorders due to its favorable physicochemical properties for blood-brain barrier penetration.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for pharmaceutical clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	2H-Pyrazolo[3,4-C]Pyridine, 4,5,6,7-Tetrahydro-2-Methyl-
CAS No.	1368187-49-8
Molecular Formula	C7H10N3
Molecular Weight	136.18 g/mol
Synonyms	4,5,6,7-Tetrahydro-2-methyl-2H-pyrazolo[3,4-c]pyridine; 2-Methyl-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-c]pyridine; 2-Methyl-2,4,5,6,7,8-hexahydropyrazolo[3,4-c]pyridine; 2-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine; Tetrahydro-2-methylpyrazolopyridine; Pyrazolo[3,4-c]pyridine, 4,5,6,7-tetrahydro-2-methyl-
EINECS	Contact for details

Quality Control

Our 2H-Pyrazolo[3,4-C]Pyridine, 4,5,6,7-Tetrahydro-2-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.