Description

5-Amino-2-Methoxy-Isonicotinic Acid Methyl Ester is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its versatile reactivity, offering both a protected carboxylic acid group and a primary amine, which makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting the central nervous system or acting as kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized to build molecular probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	5-Amino-2-Methoxy-Isonicotinic Acid Methyl Ester
CAS No.	1368183-31-6
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	Methyl 5-amino-2-methoxypyridine-4-carboxylate; 2-Methoxy-5-amino-isonicotinic acid methyl ester; 4-Pyridinecarboxylic acid, 5-amino-2-methoxy-, methyl ester; 5-Amino-2-methoxypyridine-4-carboxylic acid methyl ester; 1368183-31-6
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Methoxy-Isonicotinic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.