Description

Ethanone, 1-(2-Bromoimidazo[1,2-A]Pyridin-3-Yl)- is a high-value brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it serves as a critical precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to introduce the imidazo[1,2-a]pyridine scaffold into novel active compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides that require specific heterocyclic cores for bioactivity.
• Material Science Research: Employed as a building block for creating organic semiconductors, ligands for catalysis, and advanced functional materials.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Library Synthesis for HTS: A valuable input for generating diverse compound libraries used in high-throughput screening (HTS) campaigns to identify new lead molecules.

Basic Information

Product Name	Ethanone, 1-(2-Bromoimidazo[1,2-A]Pyridin-3-Yl)-
CAS No.	1367773-86-1
Molecular Formula	C9H7BrN2O
Molecular Weight	239.07 g/mol
Synonyms	1-(2-Bromoimidazo[1,2-a]pyridin-3-yl)ethanone; 2-Bromo-3-acetylimidazo[1,2-a]pyridine; 3-Acetyl-2-bromoimidazo[1,2-a]pyridine; Ethanone, 1-(2-bromoimidazo[1,2-a]pyridin-3-yl)-; 1367773-86-1; 2-Bromoimidazo[1,2-a]pyridin-3-yl methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Bromoimidazo[1,2-A]Pyridin-3-Yl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.