Description

3-Cyclobutoxypyridine-2-Carboxylic Acid CAS NO 1366665-04-4 is a high-purity, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the cyclobutoxy moiety into heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Key synthon for the research and development of new drug candidates, especially in kinase inhibitor and antiviral agent discovery.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Precursor for functionalized polymers or organic electronic materials due to its aromatic and carboxylic acid functionalities.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthetic projects requiring this specific heterocyclic motif.

Basic Information

Product Name	3-Cyclobutoxypyridine-2-Carboxylic Acid
CAS No.	1366665-04-4
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-cyclobutoxy-; 3-Cyclobutoxy-2-pyridinecarboxylic acid; 3-Cyclobutoxypicolinic Acid; 2-Carboxy-3-cyclobutoxypyridine; Cyclobutyl 2-carboxypyridin-3-yl ether; Picolinic acid, 3-cyclobutoxy-; 1366665-04-4 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 3-Cyclobutoxypyridine-2-Carboxylic Acid is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and supply chain reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.