Description

tert-Butyl n-{[1-(Pyridin-2-Yl)Piperidin-4-Yl]Methyl}Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine-pyridine core structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing therapeutics for central nervous system (CNS) and other disease targets.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of potential drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a key scaffold for constructing complex molecules in the development of new active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis: A starting material for contract manufacturers offering bespoke synthesis services for pharmaceutical clients.
• Process Chemistry: Used in route scouting and scale-up studies for the efficient manufacturing of target molecules.

Basic Information

Product Name	tert-Butyl n-{[1-(Pyridin-2-Yl)Piperidin-4-Yl]Methyl}Carbamate
CAS No.	1365988-39-1
Molecular Formula	C17H27N3O2
Molecular Weight	305.42 g/mol
Synonyms	tert-Butyl (1-(pyridin-2-yl)piperidin-4-yl)methylcarbamate; N-Boc-4-(aminomethyl)-1-(2-pyridyl)piperidine; 1-(Pyridin-2-yl)-4-(aminomethyl)piperidine, N-Boc protected; Boc-AMPP; tert-Butyl [(1-(2-pyridinyl)-4-piperidinyl)methyl]carbamate; Carbamic acid, N-[(1-(2-pyridinyl)-4-piperidinyl)methyl]-, 1,1-dimethylethyl ester; 4-[(tert-Butoxycarbonylamino)methyl]-1-(pyridin-2-yl)piperidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl n-{[1-(Pyridin-2-Yl)Piperidin-4-Yl]Methyl}Carbamate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are characterized and released against comprehensive specifications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is light-sensitive and should be handled and stored away from direct light. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.