Description

3-Iodo-2,5,6-Trimethoxypyridine is a high-purity, multi-functional pyridine derivative designed for advanced chemical synthesis. This compound serves as a critical building block in pharmaceutical and agrochemical research, offering a reactive iodine handle for cross-coupling reactions and a methoxy-substituted aromatic core for further functionalization. It is primarily utilized by R&D chemists and process development scientists in the life sciences and fine chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Used to create sophisticated nitrogen-containing ligands for transition metal catalysis.
• Material Science Research: Intermediate in the development of organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for Suzuki, Stille, and Sonogashira coupling reactions.
• Academic & Contract Research: Essential reagent for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	3-Iodo-2,5,6-Trimethoxypyridine
CAS No.	1364917-19-0
Molecular Formula	C8H10INO3
Molecular Weight	295.08 g/mol
Synonyms	2,5,6-Trimethoxy-3-iodopyridine; 3-Iodo-2,5,6-trimethoxypyridine; Pyridine, 3-iodo-2,5,6-trimethoxy-; Iodotrimethoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 3-Iodo-2,5,6-Trimethoxypyridine is manufactured under strict quality management systems. Our products undergo rigorous quality testing, including HPLC, NMR, and mass spectrometry, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.