Description

4-Amino-3-Bromo-2-Methyl-2H-Pyrazolo[3,4-B]Pyridine is a high-value, heterocyclic organic building block with a fused pyrazolopyridine core. This compound is essential for advanced research and development in medicinal chemistry, serving as a key synthetic intermediate for creating novel pharmacologically active molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential kinase inhibitors and other small molecule therapeutics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug candidates.
• Agrochemical Development: Serves as a precursor in the research of novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways.
• Material Science Research: Investigated as a precursor for organic electronic materials and specialty dyes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	4-Amino-3-Bromo-2-Methyl-2H-Pyrazolo[3,4-B]Pyridine
CAS No.	1363381-37-6
Molecular Formula	C8H9BrN4
Molecular Weight	241.09 g/mol
Synonyms	3-Bromo-4-amino-2-methyl-2H-pyrazolo[3,4-b]pyridine; 2H-Pyrazolo[3,4-b]pyridine, 4-amino-3-bromo-2-methyl-; 4-Amino-3-bromo-2-methylpyrazolo[3,4-b]pyridine; 4-Amino-3-bromo-2-methyl-2H-pyrazolo[3,4-b]pyridine; 1363381-37-6; AKOS026710916; 4-Amino-3-bromo-2-methyl-2H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Bromo-2-Methyl-2H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.