Description

Methyl 1H-Pyrazolo[4,3-B]Pyridine-7-Carboxylate is a high-value heterocyclic building block and pharmaceutical intermediate. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) and advanced materials, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery programs, particularly for developing kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Agrochemical Development: Used in the research and synthesis of new crop protection agents and herbicides.
• Chemical Biology Probes: Employed in the development of molecular probes for studying biological pathways and target validation.
• Material Science: Potential building block for advanced organic electronic materials and ligands in catalysis.

Basic Information

Product Name	Methyl 1H-Pyrazolo[4,3-B]Pyridine-7-Carboxylate
CAS No.	1363381-17-2
Molecular Formula	C9H7N3O2
Molecular Weight	189.17 g/mol
Synonyms	Methyl 1H-pyrazolo[4,3-b]pyridine-7-carboxylate; 1H-Pyrazolo[4,3-b]pyridine-7-carboxylic acid, methyl ester; Methyl 7-carboxy-1H-pyrazolo[4,3-b]pyridine; 7-Methoxycarbonyl-1H-pyrazolo[4,3-b]pyridine; Pyrazolopyridine-7-carboxylate methyl ester; 1363381-17-2; Methyl 1H-pyrazolo[4,3-b]pyridine-7-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 1H-Pyrazolo[4,3-B]Pyridine-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.