Description

6-Bromo-Imidazo[1,5-A]Pyridine-1-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate with the CAS number 1363380-47-5. This compound is a critical building block in modern medicinal chemistry, valued for its imidazopyridine core which is a privileged scaffold in drug discovery. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Synthesis: Incorporated into the synthetic route of complex molecules for preclinical and clinical development.
• Chemical Biology Probes: Serves as a starting material for creating tool compounds to study biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and biotech clients.
• Academic Research: Utilized in university and institutional labs for heterocyclic chemistry and synthetic methodology development.

Basic Information

Product Name	6-Bromo-Imidazo[1,5-A]Pyridine-1-Carboxylic Acid Ethyl Ester
CAS No.	1363380-47-5
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	Ethyl 6-Bromoimidazo[1,5-a]pyridine-1-carboxylate; 6-Bromo-1H-imidazo[1,5-a]pyridine-1-carboxylic acid ethyl ester; 6-Bromoimidazo[1,5-a]pyridine-1-carboxylic Acid Ethyl Ester; Imidazo[1,5-a]pyridine-1-carboxylic acid, 6-bromo-, ethyl ester; Ethyl 6-bromo-1H-imidazo[1,5-a]pyridine-1-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Bromo-Imidazo[1,5-A]Pyridine-1-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment supports applications requiring material for GLP (Good Laboratory Practice) and cGMP (current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.