Description

4-Bromo-2-(Trifluoromethoxy)Pyridine is a high-value halogenated pyridine derivative, distinguished by its bromine and trifluoromethoxy functional groups. This compound is a critical pharmaceutical intermediate and agrochemical building block, prized for its ability to impart metabolic stability and lipophilicity to target molecules. It is essential for research and development chemists in the life sciences and advanced materials sectors seeking to synthesize novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring specific halogenated aromatic units.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological mechanisms and target engagement.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethoxy)Pyridine
CAS No.	1361880-72-9
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	2-(Trifluoromethoxy)-4-bromopyridine; 4-Bromo-2-(trifluoromethoxy)pyridine; 4-Bromo-2-(trifluoromethoxy)pyridine; 4-Bromo-2-trifluoromethoxypyridine; Pyridine, 4-bromo-2-(trifluoromethoxy)-; 1361880-72-9
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-2-(Trifluoromethoxy)Pyridine adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.