Description

3-Bromo-2-Chloro-5-(Trifluoromethoxy)Pyridine is a high-purity halogenated pyridine derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique substitution pattern, which enables the precise construction of complex molecules for demanding applications. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

This specialized intermediate is designed for high-value synthesis pathways. Key application areas include:

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy and halogen groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic electronic materials, and specialty polymers.
• Chemical Research & Development: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce complex functionalities into molecular scaffolds.
• Liquid Crystal & OLED Material Precursor: Used in the development of advanced organic materials for display and lighting technologies.

Basic Information

Product Name	3-Bromo-2-Chloro-5-(Trifluoromethoxy)Pyridine
CAS No.	1361852-33-6
Molecular Formula	C6H2BrClF3NO
Molecular Weight	276.44 g/mol
Synonyms	2-Chloro-3-bromo-5-(trifluoromethoxy)pyridine; 5-(Trifluoromethoxy)-3-bromo-2-chloropyridine; 3-Bromo-2-chloro-5-(trifluoromethoxy)pyridine; Pyridine, 3-bromo-2-chloro-5-(trifluoromethoxy)-; 1361852-33-6
EINECS	Contact for details

Quality Control

Our production of 3-Bromo-2-Chloro-5-(Trifluoromethoxy)Pyridine adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot is fully characterized and analyzed using advanced techniques including HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.