Description

4-(Trifluoromethoxy)Picolinic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a picolinic acid core and a trifluoromethoxy substituent, makes it an essential intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting metabolic and central nervous system diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group can improve efficacy and environmental profile.
• Ligand for Catalysis: Serves as a precursor for creating specialized ligands used in transition metal catalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers, where fluorine incorporation modifies material properties.
• Chemical Biology Probes: Utilized as a synthetic handle for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Product Name	4-(Trifluoromethoxy)Picolinic Acid
CAS No.	1361850-00-1
Molecular Formula	C7H4F3NO3
Molecular Weight	207.11 g/mol
Synonyms	4-(Trifluoromethoxy)pyridine-2-carboxylic acid; 2-Pyridinecarboxylic acid, 4-(trifluoromethoxy)-; 4-(Trifluoromethoxy)-2-pyridinecarboxylic acid; 4-Trifluoromethoxypicolinic acid; 4-(Trifluoromethoxy)picolinate
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Picolinic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.