Description

2-(Benzyloxy)-3-Bromo-5-Iodopyridine is a high-purity, multi-halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its unique halogen substitution pattern, which provides distinct reactivity sites for selective cross-coupling and functionalization reactions. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Synthesis: Serves as a starting material for creating specialized nitrogen-containing ligands used in transition metal catalysis.
• Material Science: Employed in the research and production of organic electronic materials, such as charge-transport layers or light-emitting components.
• Cross-Coupling Reactions: An essential substrate for Suzuki, Stille, and Negishi coupling reactions due to the presence of both bromo and iodo leaving groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	2-(Benzyloxy)-3-Bromo-5-Iodopyridine
CAS No.	1361342-88-2
Molecular Formula	C12H9BrINO
Molecular Weight	389.02 g/mol
Synonyms	3-Bromo-5-iodo-2-(phenylmethoxy)pyridine; 2-(Benzyloxy)-3-bromo-5-iodopyridine; 3-Bromo-2-(benzyloxy)-5-iodopyridine; Pyridine, 3-bromo-5-iodo-2-(phenylmethoxy)-; 1361342-88-2; BBL-001 (Research Code); BBIP (Abbreviation)
EINECS	Contact for details

Quality Control

Our 2-(Benzyloxy)-3-Bromo-5-Iodopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and GC-MS for solvent residue analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under subdued lighting or amber glass when appropriate.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.