Description

Isopropyl 5-Hydroxy-2-Methyl-4-(3-Nitrophenyl)-6-Oxo-1,4,5,6-Tetrahydropyridine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in research and development pipelines targeting specific therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) or anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its functionalized tetrahydropyridine core.
• Process Chemistry Development: Employed in scaling up synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in API manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for exploring new heterocyclic chemistry and bioactivity.

Basic Information

Product Name	Isopropyl 5-Hydroxy-2-Methyl-4-(3-Nitrophenyl)-6-Oxo-1,4,5,6-Tetrahydropyridine-3-Carboxylate
CAS No.	1360462-97-0
Molecular Formula	C16H18N2O6
Molecular Weight	334.33 g/mol
Synonyms	5-Hydroxy-2-methyl-4-(3-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid isopropyl ester; Isopropyl 5-hydroxy-2-methyl-4-(3-nitrophenyl)-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylate; 1,4,5,6-Tetrahydropyridine-3-carboxylic acid, 5-hydroxy-2-methyl-4-(3-nitrophenyl)-6-oxo-, 1-methylethyl ester; 1360462-97-0; 4-(3-Nitrophenyl)-5-hydroxy-2-methyl-6-oxo-1,4,5,6-tetrahydropyridine-3-carboxylic acid isopropyl ester
EINECS	Contact for details

Quality Control

Our Isopropyl 5-Hydroxy-2-Methyl-4-(3-Nitrophenyl)-6-Oxo-1,4,5,6-Tetrahydropyridine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures material suitable for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.