Description

Pyrido[3,2-F]-1,4-Oxazepin-5(2H)-One, 8-Chloro-3,4-Dihydro-4-(Phenylmethyl)- is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. Pharmaceutical manufacturers, contract research organizations (CROs), and academic research institutions need it to develop next-generation therapeutic agents, relying on its consistent quality and reliable supply chain to accelerate drug discovery and development pipelines.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates targeting specific biological pathways.
• CNS Drug Research: Used in the research and development of novel therapeutics for neurological and psychiatric disorders, leveraging its fused oxazepine-pyridine scaffold.
• Oncology Research: Employed as a building block for creating potential kinase inhibitors and other targeted anti-cancer agents.
• Medicinal Chemistry: Provides a versatile chemical handle for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant production of clinical trial materials.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental research in heterocyclic chemistry and pharmacology.

Basic Information

Product Name	Pyrido[3,2-F]-1,4-Oxazepin-5(2H)-One, 8-Chloro-3,4-Dihydro-4-(Phenylmethyl)-
CAS No.	1360437-75-7
Molecular Formula	C17H15ClN2O2
Molecular Weight	314.77 g/mol
Synonyms	8-Chloro-3,4-dihydro-4-(phenylmethyl)pyrido[3,2-f][1,4]oxazepin-5(2H)-one; 8-Chloro-4-benzyl-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepin-5-one; 1360437-75-7; 4-Benzyl-8-chloro-2,3,4,5-tetrahydropyrido[3,2-f][1,4]oxazepin-5-one; Pyrido[3,2-f][1,4]oxazepin-5(2H)-one, 8-chloro-3,4-dihydro-4-(phenylmethyl)-
EINECS	Contact for details

Quality Control

Our Pyrido[3,2-F]-1,4-Oxazepin-5(2H)-One, 8-Chloro-3,4-Dihydro-4-(Phenylmethyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.