Description

Lapatinib CAS NO 1360431-86-2 is a potent and selective small-molecule dual tyrosine kinase inhibitor. This compound is of significant commercial and research interest for its targeted therapeutic action. It is primarily required by pharmaceutical R&D departments, contract manufacturing organizations (CMOs), and academic research institutions focused on oncology and kinase signaling pathways.

Application

• Active Pharmaceutical Ingredient (API) in the formulation of targeted cancer therapies.
• Reference Standard for quality control and analytical method development in pharmaceutical laboratories.
• Biochemical Research tool for studying the ErbB/EGFR and HER2/neu signaling pathways in cellular models.
• Pre-clinical Development for efficacy and pharmacokinetic studies in oncology drug discovery programs.
• Process Chemistry and intermediate synthesis for scale-up and manufacturing process optimization.

Basic Information

Product Name	Lapatinib
CAS No.	1360431-86-2
Molecular Formula	C₂₉H₂₆ClFN₄O₄S
Molecular Weight	581.06 g/mol
Synonyms	Lapatinib Ditosylate; GW572016; Tykerb; Tyverb; N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine; GW2016; Lapatinib Ditosylate Monohydrate
EINECS	Contact for details

Quality Control

Our Lapatinib is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, confirming compliance with in-house specifications and supporting its use in research and development. We adhere to cGMP principles where applicable to ensure reliable supply for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.