Description

1H-Imidazo[4,5-C]Quinolin-4-Amine, 1-(4-Aminobutoxy)-2-Butyl- CAS NO 1359993-63-7 is a high-purity, advanced pharmaceutical intermediate belonging to the imidazoquinoline class of heterocyclic compounds. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel therapeutic agents, particularly immunomodulators and antiviral drugs. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of next-generation small-molecule therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of Toll-like receptor (TLR) agonists and other immunostimulatory compounds.
• Drug Discovery & Development: Used in medicinal chemistry research for creating new chemical entities (NCEs) targeting viral infections and autoimmune disorders.
• Active Pharmaceutical Ingredient (API) Synthesis: A key raw material in the multi-step manufacturing process of final drug substances.
• Biochemical Research: Employed in academic and industrial labs for studying immune response pathways and structure-activity relationships (SAR).
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	1H-Imidazo[4,5-C]Quinolin-4-Amine, 1-(4-Aminobutoxy)-2-Butyl-
CAS No.	1359993-63-7
Molecular Formula	C₁₈H₂₅N₅O
Molecular Weight	327.43 g/mol
Synonyms	1-(4-Aminobutoxy)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine; 2-Butyl-1-(4-aminobutoxy)-1H-imidazo[4,5-c]quinolin-4-amine; 1H-Imidazo[4,5-c]quinolin-4-amine, 1-(4-aminobutoxy)-2-butyl-; TLR7/8 Agonist Intermediate; Imidazoquinoline amine derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to stringent quality protocols suitable for pharmaceutical applications. Every batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring full traceability and compliance with your internal specifications and the principles of current Good Manufacturing Practice (cGMP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Ensure the storage area is well-ventilated and separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.