Description

2-Bromo-1-Cyclopropyl-2-(4-Fluorophenyl)Ethanone is a high-purity, advanced pharmaceutical intermediate featuring a unique halogenated ketone structure. This compound is critical for facilitating key synthetic transformations, particularly in the construction of complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its fluorinated aromatic and reactive bromo-ketone moiety.
• Chemical Synthesis: Serves as a versatile electrophile in cross-coupling reactions, nucleophilic substitutions, and cyclization processes to create novel heterocyclic compounds.
• Material Science Precursor: Potential use in the synthesis of specialized ligands, catalysts, or monomers for advanced polymeric materials.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	2-Bromo-1-Cyclopropyl-2-(4-Fluorophenyl)Ethanone
CAS No.	1359829-52-9
Molecular Formula	C11H10BrFO
Molecular Weight	257.10 g/mol
Synonyms	2-Bromo-1-cyclopropyl-2-(4-fluorophenyl)ethan-1-one; 2-Bromo-1-cyclopropyl-2-(p-fluorophenyl)ethanone; α-Bromo-4-fluorocyclopropyl phenyl ketone; 4-Fluoro-α-(bromoacetyl)benzene cyclopropane derivative; (4-Fluorophenyl)(cyclopropyl) bromomethyl ketone; Bromo(4-fluorophenyl)(cyclopropyl)methanone; CAS 1359829-52-9
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Cyclopropyl-2-(4-Fluorophenyl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.