Description

1-Bromo-3-Fluoro-2-(1H-Pyrazol-1-Ylmethyl)Benzene is a high-value, multi-functional aromatic building block designed for advanced synthetic chemistry. This compound matters because its unique structure, featuring bromo, fluoro, and pyrazolylmethyl substituents, provides versatile reactivity for constructing complex molecular architectures. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the pyrazole moiety.
• Ligand Synthesis: Serves as a versatile scaffold for constructing complex chelating ligands in catalysis and material science.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization due to its modifiable halogen and heterocyclic groups.
• Material Science Precursor: Potential building block for organic electronic materials and functional polymers.
• Cross-Coupling Reactions: The bromo substituent makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.

Basic Information

Product Name	1-Bromo-3-Fluoro-2-(1H-Pyrazol-1-Ylmethyl)Benzene
CAS No.	1355247-09-4
Molecular Formula	C10H8BrFN2
Molecular Weight	255.09 g/mol
Synonyms	1-Bromo-3-fluoro-2-(1H-pyrazol-1-ylmethyl)benzene; 2-(1H-Pyrazol-1-ylmethyl)-1-bromo-3-fluorobenzene; 1-(2-Bromo-6-fluorobenzyl)-1H-pyrazole; Benzene, 1-bromo-3-fluoro-2-(1H-pyrazol-1-ylmethyl)-; 1-Bromo-3-fluoro-2-(pyrazol-1-ylmethyl)benzene; 1-Bromo-3-fluoro-2-((1H-pyrazol-1-yl)methyl)benzene
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide comprehensive analytical data including HPLC, GC, NMR, and mass spectrometry to verify identity and purity. Certificates of Analysis (COA) are available upon request, detailing batch-specific results for all critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.