Description

Ethyl 3-Bromo-8-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-2-Carboxylate is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound matters because it provides a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this intermediate for its unique trifluoromethyl and bromo substituents, which are critical for modulating the biological activity, metabolic stability, and physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Research: Used to develop new generations of herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a building block for creating advanced organic electronic materials and functional dyes.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for biological target validation.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies and lead optimization programs due to its reactive bromo site.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.

Basic Information

Product Name	Ethyl 3-Bromo-8-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-2-Carboxylate
CAS No.	1355171-40-2
Molecular Formula	C11H7BrF3N2O2
Molecular Weight	333.09 g/mol
Synonyms	Ethyl 3-bromo-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate; 3-Bromo-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylic acid, 3-bromo-8-(trifluoromethyl)-, ethyl ester; 1355171-40-2; Ethyl 3-bromo-8-trifluoromethylimidazo[1,2-a]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-8-(Trifluoromethyl)Imidazo-[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and traceability ensures you receive a reliable, high-purity intermediate for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.