Description

Ethyl 3-Bromo-8-Chloro-6-(Trifluoromethyl)-Imidazo[1,2-A]Pyridine-2-Carboxylate is a high-value, multi-functionalized heterocyclic building block designed for advanced synthetic chemistry. Its core value lies in providing a versatile scaffold for constructing complex molecules, particularly in the development of novel active pharmaceutical ingredients (APIs). This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require precise, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology therapeutics.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, leveraging its halogenated and trifluoromethyl-substituted structure for enhanced bioactivity.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study biological pathways and protein functions.
• Material Science: Potential building block for organic electronic materials and specialty polymers due to its fused imidazopyridine core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specific molecular architecture.

Basic Information

Product Name	Ethyl 3-Bromo-8-Chloro-6-(Trifluoromethyl)-Imidazo[1,2-A]Pyridine-2-Carboxylate
CAS No.	1355170-29-4
Molecular Formula	C11H7BrClF3N2O2
Molecular Weight	371.54 g/mol
Synonyms	Ethyl 3-bromo-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylate; 2-Imidazo[1,2-a]pyridinecarboxylic acid, 3-bromo-8-chloro-6-(trifluoromethyl)-, ethyl ester; 1355170-29-4; 3-Bromo-8-chloro-6-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester; Imidazo[1,2-a]pyridine-2-carboxylate derivative (BCTFIP ester).
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-8-Chloro-6-(Trifluoromethyl)-Imidazo[1,2-A]Pyridine-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and aligns with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.