Description

n-Ethyl-N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate and building block featuring a pinacol boronate ester functional group. This compound is critical for modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) for drug discovery and development.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for forming carbon-carbon bonds between aromatic and heteroaromatic systems.
• Agrochemical Research: Used in the creation of novel herbicides, fungicides, and insecticides requiring specific pyridine-based architectures.
• Material Science: A precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugation reagents.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific synthesis projects.

Basic Information

Product Name	n-Ethyl-N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1354727-04-0
Molecular Formula	C15H25BN2O2
Molecular Weight	276.19 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethyl-N,3-dimethylpyridin-2-amine; 2-Amino-N-ethyl-N,3-dimethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; N-Ethyl-N,3-dimethyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 1354727-04-0; Pinacol [5-[(ethylmethylamino)methyl]-3-methyl-2-pyridinyl]boronate; Boronic acid, B-[5-[(ethylmethylamino)methyl]-3-methyl-2-pyridinyl]-, pinacol ester
EINECS	Contact for details

Quality Control

Our n-Ethyl-N,3-Dimethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.