Description

5-(3-Azidopropyl)Uridine is a modified nucleoside analog featuring a reactive azide group, making it a versatile building block for click chemistry applications. This compound is essential for researchers and manufacturers developing novel oligonucleotide conjugates, probes, and targeted drug delivery systems. It is primarily utilized in the pharmaceutical, biotechnology, and life sciences research sectors for applications such as bioconjugation, nucleic acid labeling, and chemical biology studies.

Application

• Key intermediate in the synthesis of click chemistry-compatible nucleoside triphosphates for enzymatic incorporation into nucleic acids.
• Building block for the preparation of azide-functionalized oligonucleotides used in bioorthogonal labeling and detection.
• Critical reagent in the development of targeted therapeutic conjugates, including antibody-drug conjugates (ADCs) and siRNA delivery vehicles.
• Chemical probe for metabolic labeling and imaging of cellular RNA in advanced research applications.
• Precursor for cross-linking agents and materials used in nucleic acid nanotechnology and surface functionalization.
• Tool compound in medicinal chemistry for the discovery of novel antiviral and anticancer nucleoside analogs.

Basic Information

Product Name	5-(3-Azidopropyl)Uridine
CAS No.	1354419-08-1
Molecular Formula	C12H15N5O6
Molecular Weight	325.28 g/mol
Synonyms	5-(3-Azidopropyl)uridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-(3-azidopropyl)pyrimidine-2,4(1H,3H)-dione; Uridine, 5-(3-azidopropyl)-; 5-N-(3-Azidopropyl)uridine; Azide-PEG3-Uridine
EINECS	Contact for details

Quality Control

Our 5-(3-Azidopropyl)Uridine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee reproducibility and traceability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider keeping the material desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.