Description

[1-((E)-4-Phenyl-But-3-Enyl)-Piperidin-3-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system. It is primarily needed by research institutions, custom synthesis houses, and pharmaceutical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, especially in neurological and psychiatric therapeutic areas.
• Custom Synthesis & Contract Manufacturing: Serves as a specialized starting material or intermediate for custom chemical synthesis projects and outsourced API manufacturing.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during early-stage drug discovery.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	[1-((E)-4-Phenyl-But-3-Enyl)-Piperidin-3-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353990-98-3
Molecular Formula	C20H30N2O2
Molecular Weight	330.47 g/mol
Synonyms	tert-Butyl N-[1-[(E)-4-phenylbut-3-en-1-yl]-3-piperidinyl]carbamate; 1-[(1E)-4-Phenyl-1-buten-1-yl]-3-piperidinecarboxylic acid 1,1-dimethylethyl ester; BOC-Piperidine intermediate; (E)-tert-Butyl (1-(4-phenylbut-3-en-1-yl)piperidin-3-yl)carbamate; 3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[(1E)-4-phenyl-1-buten-1-yl]piperidine; N-BOC-3-Amino-1-[(E)-4-phenyl-3-butenyl]piperidine
EINECS	Contact for details

Quality Control

Our [1-((E)-4-Phenyl-But-3-Enyl)-Piperidin-3-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.