Description

(2-Aminomethyl-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize pharmacological properties.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients, particularly those with piperidine and benzodioxane motifs.
• Biochemical Tool Compound: May be utilized in vitro as a ligand or probe to study specific biological receptors or pathways in preclinical research.
• Process Chemistry: Acts as a standard or reference material for analytical method development and validation during API manufacturing.

Basic Information

Product Name	(2-Aminomethyl-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride
CAS No.	1353985-86-0
Molecular Formula	C16H21N2O3·HCl
Molecular Weight	332.81 g/mol (Free base: 289.35 g/mol)
Synonyms	1-[(2,3-Dihydro-1,4-benzodioxin-2-yl)carbonyl]-2-(aminomethyl)piperidine hydrochloride; 2-[(Aminomethyl)piperidin-1-yl](2,3-dihydro-1,4-benzodioxin-2-yl)methanone hydrochloride; (2,3-Dihydrobenzo[b][1,4]dioxin-2-yl)(2-(aminomethyl)piperidin-1-yl)methanone HCl; Benzodioxanyl piperidinyl methanone hydrochloride derivative
EINECS	Contact for details

Quality Control

Our (2-Aminomethyl-Piperidin-1-Yl)-(2,3-Dihydro-Benzo[1,4]Dioxin-2-Yl)-Methanone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%; Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.