Description

(2-Bromopyridin-4-Yl)Methanamine Hydrochloride CAS NO 1353979-69-7 is a high-purity, halogenated pyridine derivative used as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, offering both a reactive bromine atom and a primary amine group, protected as a stable hydrochloride salt, for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands in transition metal catalysis and organometallic chemistry.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science Research: Acts as a monomer or functionalization agent in the development of advanced polymers and functional organic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this specific bromopyridine scaffold.

Basic Information

Product Name	(2-Bromopyridin-4-Yl)Methanamine Hydrochloride
CAS No.	1353979-69-7
Molecular Formula	C6H8BrClN2
Molecular Weight	223.50 g/mol
Synonyms	4-(Aminomethyl)-2-bromopyridine hydrochloride; 2-Bromo-4-(aminomethyl)pyridine hydrochloride; (2-Bromo-4-pyridinyl)methanamine hydrochloride; 1-(2-Bromopyridin-4-yl)methanamine hydrochloride; 2-Bromo-4-pyridinemethanamine hydrochloride; 4-(Aminomethyl)-2-bromopyridine HCl; 2-Bromo-4-(aminomethyl)pyridine HCl
EINECS	Contact for details

Quality Control

Every batch of (2-Bromopyridin-4-Yl)Methanamine Hydrochloride is produced and tested under strict quality management protocols to ensure consistency and reliability for research and scale-up. We provide comprehensive analytical data, including HPLC purity, NMR confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is available for each lot upon request, supporting regulatory filings and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.