Description

2-Chloro-n-Piperidin-3-Yl-Nicotinamide Hydrochloride is a high-purity chemical building block and advanced pharmaceutical intermediate. This compound is valued for its role in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers targeting novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Chemical Biology Probes: Serves as a precursor for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Library Synthesis: Used to create diverse compound libraries for high-throughput screening in drug discovery.

Basic Information

Item	Details
Product Name	2-Chloro-n-Piperidin-3-Yl-Nicotinamide Hydrochloride
CAS No.	1353972-64-1
Molecular Formula	C11H15ClN3O • HCl
Molecular Weight	278.17 g/mol
Synonyms	2-Chloro-N-(3-piperidinyl)nicotinamide hydrochloride; 2-Chloro-N-(piperidin-3-yl)pyridine-3-carboxamide hydrochloride; 3-Pyridinecarboxamide, 2-chloro-N-3-piperidinyl-, hydrochloride; 2-Chloro-N-(3-piperidinyl)nicotinamide HCl; Nicotinamide, 2-chloro-N-(3-piperidinyl)-, hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-n-Piperidin-3-Yl-Nicotinamide Hydrochloride is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. All products are supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support pharmaceutical development workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.