Description

(4-Methyl-Benzyl)-Piperidin-3-Yl-Amine Hydrochloride is a high-purity organic salt compound with the CAS registry number 1353955-95-9. This specialized chemical building block is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for creating new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug candidates, particularly in central nervous system (CNS) and receptor-targeted therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Used in the scale-up and optimization of synthetic routes for potential active pharmaceutical ingredients (APIs).
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for the contract manufacturing of specialized, non-commercial fine chemicals and advanced intermediates.

Basic Information

Product Name	(4-Methyl-Benzyl)-Piperidin-3-Yl-Amine Hydrochloride
CAS No.	1353955-95-9
Molecular Formula	C14H23ClN2
Molecular Weight	254.80 g/mol
Synonyms	1-[(4-Methylphenyl)methyl]-3-piperidinamine hydrochloride; 3-Amino-1-(4-methylbenzyl)piperidine hydrochloride; 1-(4-Methylbenzyl)piperidin-3-amine hydrochloride; (4-Methylbenzyl)(3-aminopiperidin-1-yl)methanone hydrochloride (tautomer); 4-Methylbenzyl-piperidin-3-yl-amine HCl; 3-Piperidinamine, 1-[(4-methylphenyl)methyl]-, hydrochloride; 1-(p-Tolylmethyl)piperidin-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (4-Methyl-Benzyl)-Piperidin-3-Yl-Amine Hydrochloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. Our products are validated to meet the stringent purity requirements for pharmaceutical R&D applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles via techniques such as HPLC, NMR, and mass spectrometry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.