Description

(6-Bromo-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine Hydrochloride CAS NO 1353953-53-3 is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyridine and cyclopropylamine hydrochloride structure. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel, targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of small-molecule drugs, particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) for investigational new drugs.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand Synthesis: Used in the preparation of specialized ligands for biological target modulation and receptor studies.
• Chemical Biology Probes: Employed in the development of molecular probes for investigating enzyme function and cellular pathways.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.

Basic Information

Product Name	(6-Bromo-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine Hydrochloride
CAS No.	1353953-53-3
Molecular Formula	C9H12BrClN2
Molecular Weight	263.56 g/mol
Synonyms	1-(6-Bromopyridin-3-yl)-N-cyclopropylmethanamine hydrochloride; Cyclopropyl-(6-bromopyridin-3-ylmethyl)amine hydrochloride; 6-Bromo-3-((cyclopropylamino)methyl)pyridine hydrochloride; (6-Bromo-3-pyridylmethyl)cyclopropylamine hydrochloride; N-[(6-Bromopyridin-3-yl)methyl]cyclopropanamine hydrochloride; 3-((Cyclopropylamino)methyl)-6-bromopyridine hydrochloride
EINECS	Contact for details

Quality Control

Our (6-Bromo-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP (current Good Manufacturing Practice) standards for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.