Description

(6-Chloro-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure, essential for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters as a critical building block in medicinal chemistry, enabling the development of targeted therapeutic agents with potential applications in central nervous system (CNS) and other disease areas. It is primarily needed by R&D chemists, process development scientists, and manufacturers in the global pharmaceutical and agrochemical industries for creating next-generation compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for CNS-targeted therapies.
• Agrochemical Synthesis: Used as a precursor in the manufacture of advanced crop protection agents and pesticides.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry: Employed in scale-up and route development for the commercial production of complex organic molecules.
• Chemical Biology Probes: Can be utilized in the development of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	(6-Chloro-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine Hydrochloride
CAS No.	1353944-89-4
Molecular Formula	C9H12Cl2N2
Molecular Weight	219.11 g/mol
Synonyms	1-(6-Chloropyridin-3-yl)-N-cyclopropylmethanamine hydrochloride; Cyclopropyl-(6-chloropyridin-3-ylmethyl)amine hydrochloride; (6-Chloro-3-pyridylmethyl)cyclopropylamine hydrochloride; 6-Chloro-3-[(cyclopropylamino)methyl]pyridine hydrochloride; N-[(6-Chloro-3-pyridinyl)methyl]cyclopropanamine hydrochloride; 1-(6-Chloro-3-pyridinyl)-N-cyclopropylmethanamine HCl
EINECS	Contact for details

Quality Control

Our (6-Chloro-Pyridin-3-Ylmethyl)-Cyclopropyl-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.