Description

4-Iodo-2-Phenoxypyridine is a versatile halogenated pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both an iodine atom and a phenoxy group, makes it a valuable building block for constructing complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for chemists and R&D teams in the life sciences, fine chemical, and material science industries who require high-purity, functionalized heterocycles for coupling reactions and molecular design.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science: Building block for creating functional organic materials, such as liquid crystals and organic semiconductors.
• Cross-Coupling Reactions: Serves as an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the reactive iodine moiety.
• Ligand Synthesis: Intermediate for the preparation of complex nitrogen-containing ligands used in catalysis.
• Chemical Biology: Used in the synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	4-Iodo-2-Phenoxypyridine
CAS No.	1353776-69-8
Molecular Formula	C11H8INO
Molecular Weight	313.10 g/mol
Synonyms	2-Phenoxy-4-iodopyridine; 4-Iodo-2-phenoxypyridine; 4-Iodo-2-phenoxy-pyridine; Pyridine, 4-iodo-2-phenoxy-; 1353776-69-8
EINECS	Contact for details

Quality Control

Our 4-Iodo-2-Phenoxypyridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and documentation for regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.