Description

2'-Deoxy-N2-Cyclopentyl Guanosine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and intermediate in the synthesis of novel therapeutic agents, particularly in the fields of antiviral and anticancer drug discovery. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing nucleotide-based therapies and molecular probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside analog drugs targeting viral polymerases.
• Antiviral Drug Research: Building block for developing potential therapeutics against DNA viruses, such as herpesviruses and hepatitis B virus (HBV).
• Oncology Research: Used in the design and synthesis of experimental chemotherapeutic agents that interfere with DNA replication in cancer cells.
• Biochemical Tool: Serves as a modified substrate for enzymatic studies to understand polymerase fidelity and mechanism.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies to optimize the potency and selectivity of guanosine-based compounds.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2'-Deoxy-N2-Cyclopentyl Guanosine
CAS No.	1353757-90-0
Molecular Formula	C15H21N5O4
Molecular Weight	335.36 g/mol
Synonyms	N2-Cyclopentyl-2'-deoxyguanosine; 2'-Deoxy-N2-cyclopentylguanosine; 9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-N-cyclopentyl-6-oxo-1H-purin-2-amine; 2'-Deoxyguanosine, N2-cyclopentyl-; Cyclopentyl-dG; dG-Cp
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-N2-Cyclopentyl Guanosine is manufactured under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.