Description

3-Bromo-5-Fluoroisonicotinamide is a high-purity fluorinated and brominated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated structure makes it an indispensable intermediate for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging its halogenated pyridine core.
• Chemical Biology Probe: Serves as a versatile scaffold for creating molecular probes to study biological pathways and protein functions.
• Material Science: Building block for synthesizing specialized ligands, catalysts, and functionalized polymers.
• Contract Research & Development (CRO/CMO): Essential raw material for custom synthesis and scale-up projects in outsourcing facilities.

Basic Information

Product Name	3-Bromo-5-Fluoroisonicotinamide
CAS No.	1353636-72-2
Molecular Formula	C6H4BrFN2O
Molecular Weight	219.01 g/mol
Synonyms	3-Bromo-5-fluoropyridine-4-carboxamide; 5-Fluoro-3-bromoisonicotinamide; 4-Pyridinecarboxamide, 3-bromo-5-fluoro-; 3-Bromo-5-fluoro-4-pyridinecarboxamide; 3-Bromo-5-fluoropyridine-4-carboxylic acid amide; 1353636-72-2; 3-Br-5-F-isonicotinamide
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Fluoroisonicotinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.