Description

3-Iodo-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine is a high-value halogenated heterocyclic building block, a key intermediate in modern pharmaceutical and agrochemical research. Its core value lies in enabling the synthesis of complex molecules through versatile cross-coupling reactions, such as Suzuki and Sonogashira couplings. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical industry developing new active pharmaceutical ingredients (APIs), particularly in kinase inhibitor programs.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Used to construct core scaffolds for potential kinase inhibitors due to the pyrazolopyridine structure.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides.
• Material Science: Potential use in the synthesis of organic electronic materials and ligands for catalysis.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed reactions to create more complex molecular architectures.
• Chemical Biology: Used as a probe or tag in biochemical research due to its specific reactivity and structure.

Basic Information

Product Name	3-Iodo-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine
CAS No.	1352396-72-5
Molecular Formula	C7H6IN3
Molecular Weight	259.05 g/mol
Synonyms	3-Iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine; 6-Methyl-3-iodo-1H-pyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 3-iodo-6-methyl-; 3-Iodo-6-methyl-pyrazolo[3,4-b]pyridine; 3-Iodo-6-methyl-1H-pyrazolo[3,4-b]pyridin; 1352396-72-5; 3-Iodo-6-methyl-1H-pyrazolo[3,4-b]pyridine (CAS 1352396-72-5)
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-Methyl-1H-Pyrazolo[3,4-B]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.