Description

tert-Butyl n-[4-(3-Cyanopyridin-2-Yl)Phenyl]Carbamate is a high-purity organic intermediate featuring a carbamate-protected aniline linked to a cyano-substituted pyridine ring. This compound is valued for its role as a critical building block in the synthesis of complex pharmaceutical molecules, particularly kinase inhibitors. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of targeted therapeutic agents, especially protein kinase inhibitors.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Chemical Synthesis Building Block: Serves as a versatile scaffold for constructing more complex heterocyclic compounds in organic chemistry.
• Active Pharmaceutical Ingredient (API) Development: Employed in the development and scale-up processes for new chemical entities (NCEs).
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study enzyme function and signaling pathways.

Basic Information

Product Name	tert-Butyl n-[4-(3-Cyanopyridin-2-Yl)Phenyl]Carbamate
CAS No.	1352318-65-0
Molecular Formula	C17H17N3O2
Molecular Weight	295.34 g/mol
Synonyms	tert-Butyl (4-(3-cyanopyridin-2-yl)phenyl)carbamate; 2-(4-((tert-Butoxycarbonyl)amino)phenyl)nicotinonitrile; Carbamic acid, N-[4-(3-cyano-2-pyridinyl)phenyl]-, 1,1-dimethylethyl ester; BOC-Protected 2-(4-Aminophenyl)nicotinonitrile; tert-Butyl 4-(3-cyanopyridin-2-yl)phenylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[4-(3-Cyanopyridin-2-Yl)Phenyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.